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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e280fa1d363f5b0efc2f7d222bb47e907ee13cbff94b555f09be318d82114d49' 
  AND token = 'X+V+SMP3k0HBfEgs8GLghXSM/+leoJtk+fzx+2ASF6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}