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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f99543eb4f52dd439d160ce431108d69d8d60fa2405c29989a6055cb46929554' 
  AND token = 'WacSOpv2KvljAdLUi6Q7O0lKFuQDLIlYuVANMNHFIG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}