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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5255e868fe22d14a53825e58a8617cb3573fea2d97b2cb79d27c68d3e21a92e' 
  AND token = 'QvTewGsatSY8NbZUCPZT4RQi0lx12vqfylhlKdoCpKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}