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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e67be247319ebb28b714b54a135b19bd4549d4d2ca8515b36da53cc7aca3a9b' 
  AND token = 'Iz1bw8eUz1gWRk1bmY285tiJq9oZVVhRaDZCoj32Ozc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}