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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456a43b7fd800c0986035f6616f62e76d5113501f1b27d3e39d9ac648db48cbc' 
  AND token = 'OBKF6bDmpRpVMMLpmoyZdP1MZRgwRLCipUEQHPuIVcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}