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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a71bd3d9665db16b98abc8a9c00fd4454484d458eb7337046f50cb365f7a2e0' 
  AND token = 'i8F1ABg5I+vnIkgdj+PQXHMdHukcUZ6pW1o6hmUaOzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}