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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9f538e24692cf9fd2230025fa4d09abb2669dfb4f17a85ca3830c2688628b42' 
  AND token = 'ToaO+8x6Te0fF5WrTqUx/c2TV/HgacYWxRQkQuoi3/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}