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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ff5a4a240171b042bd2bfa2a9fd2dfe57b0426e77e7071625b0db255d8ba66' 
  AND token = 'oXCWy7iWC/H0mEXB/75xURHsKDIIb3tmMNqDDmAs758=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}