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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457dae576a3db495a3c6b938f2510f9cf9e93a00e4603a222e2142455d9e12fd' 
  AND token = 'jnNZEp2zC0fOrOV1/LhjKO9yiOi0hWhMA24tKIOPCQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}