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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580a358140c104e9180f43b2ba33e1039a4f43bcfed602d89576d35536158416' 
  AND token = '9GBIB5KHUz655SD2iK/9/S32mmNm/Sz3Vd31c/Wkhbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}