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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a91be6b95e8c6b8e7acc29a02ca805fef2daf7df928ba445d1eb1acdd21bcadb' 
  AND token = 'pcUzUHI/wH4Ox2HUPrWJNzoCTjFMJwL1JE6y5olMJzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}