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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fe209af466dfb27ee32d2aa37a5e137eef76f76cb60bd3851acde27fca9ba1' 
  AND token = 'd7h8m1kfeNjvAFmmXXizkAU1bQ87RmgtlOqcO9CnhUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}