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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18ceeed480fc0855f9a68eab4d79e5a8813fb5fbbf13b01746f94c72b76bba3' 
  AND token = 'nDAdxmtMHhhau9+cV7zTFP6G90e4tP9JUAQSLhDuW+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}