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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7d5c2340e44c21d9d17f7c4afa481bab28f96d038d9fcfe2509146dfb6b492' 
  AND token = 'm7bixaSDEpyElp15Lw43cNO9AidOrSfL3hjThPnG8qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}