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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a80901c68a23b463750cd2aaf0fb4f82f0c3fe339b892a189d5bbe014f1788' 
  AND token = '9HRQr0hF7dTSliKtmTXmB/bQcXX5hIpjkuovpc0dG3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}