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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f782e718d1e32b6957d3ecad031b1a149a576660bc3e1ab4ca57acbf49957319' 
  AND token = 'gy5pkMdIpxkZaFsJFnyaFoEkIeJcbzXLUmfEgfpj/1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}