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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a567931cee3a2f8c5b8688bb226f69a7782499ef65808ea236ea839b85d45ec4' 
  AND token = 'axkmRqlfzdi+OtbhxWNsjaK8dVBBy8ek/4Tgpf1cAEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}