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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88050466868bf90b8370b31fa5accd8dc5b067044e6bbdc187ca825e58cf3abf' 
  AND token = 'Es/2lXpb7yTrQHe7yNHTEoGChyRjx4USnguGgnvk6tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}