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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3785c3e58806be8b8ad4de7732f48c4569a2cb1928804bdd50890169f6e5444e' 
  AND token = '/d/xM96npOjtMVKod5AgXKN9in+j8ZiCxQbhKTCuaBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}