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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f209ace8ce5a890084e10f6ef99a77aba72f01c1be098f8dbc593819689d79a' 
  AND token = 'JA3PxTq/LVklou58r3/cvltCl05GMUdct69CMj7Qs+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}