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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a12844afb06e8a72b4da28edf2f279d5ad966286a8b148448fe8c2855a1c304' 
  AND token = '5zaCcRixOaJEy6tcM9IfspPPgciVB1WZBWDR2SWeOdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}