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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59106b1a7a98488338b296836b7babe194b9416eae90eb0073996d6006d16cd9' 
  AND token = '+1x++OwnoEu81V1jqaNkuO9PJ0jt8v9idvjhYdzPP8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}