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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8488bc3b688fb67c11711210ba6d6fb842254e05f5d15533413112e390c4cf24' 
  AND token = 'Gc2dijpAA/Pt6fEmv2qeif4IP+VfeKHy604AZDiIV1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}