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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1139c496a2f52fbafe1755c4ce1ddf57d934ace7ab8d5b3be98aad9f72cb5d86' 
  AND token = 'HBJ7/8dzpBIz0EE47dTmZQQa7kI4XJ2ncsa1eVBkhjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}