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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3808c42bfd90c68cfbc4b72011d4572d61185d03cf7d27bcf3892d4e4b25e313' 
  AND token = 'hUeys9mX2TJ4WjzzgUKAhwZUNtP0Mshrx+eiWYOQQdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}