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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454dcbed7f5a4c25580d33a19f0140e24fee04cb64df3dbd290ec943ff4680ec' 
  AND token = 'UNZXsBLFSoD4MS/ooVML+e67V1j76RRG3IdIv5UlI7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}