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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cbc793f5ddd19ee8ff1dace76c0e2133724cb5f714e18809aaeea0367a02c4e' 
  AND token = '7UMQdJnQ1Ux1Je9YSjpNsrvBQsEcqLqYZr3W8JT2U+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}