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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d74122e3bb4e55f2018a43085675a681116fc4ef67a0c3e443d09f0c322e334' 
  AND token = '2bsq4CezaiGgyLsnHtCiRWs/b6Y6Frpy0BZKD6/wCIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}