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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f4ba076981334427d74d38beaec9239c0d7abb4214aeeb25f976d854ae8eaf5' 
  AND token = 'j2s1UbdVAK30y//hl9o2vTiM1wHmqeUKAKZaQxw0jPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}