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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '994ec66d851eefd509d5cec05c396bb5d827887d44eac6e132c0222b3f0767f1' 
  AND token = '+1ctNqSqhd6ZzTDq82sSp8BRI9iZfnKgNcDno48uNCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}