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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aef69d1be5f22cd0622bc33c38167bcc22ce6a5690c9a53637122aa990042d3' 
  AND token = 'xy4yorMyb3YyWKnC2MYifdrfru3T0ES5NBA/bSzJSMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}