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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dbdb81a58e8987a42e894c036e1681d6054d3f40cb329480fc1b7e4163352ec' 
  AND token = 'PNOIBkZ6JLOJCOxEkvUqRuBh1f9I+puThLg8pUi17k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}