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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ef77cee236d077fb0dc8bc8d0c87a31333027cd81ba9482e9b1b272423cccb' 
  AND token = 't00JQaa/N/HdNAWHEdCK/6wPrRaV6W82Brg1MRFJm3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}