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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '019ea1b1eed3130120bb68a942ea69f416a703b3e4250e109c4d58b9d3cfe379' 
  AND token = 'RISgBGQB0QU9BQmTaZ9B6hEdPbFceJ6V0FUZXKyg7WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}