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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a391455d80291ba23ab79e6f53da9e0d4e72e4bdd87286b52a2b9088a4238f2f' 
  AND token = 'cVLMJyB1OOSkzAOIjoAB8wBTyLn0o0xwfv4glSoJzpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}