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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5433e07e363e4fa620730ca297d432013d2bdbe7711c01d19c2b5cde47c0a0fc' 
  AND token = '29fVKh/R/4fqEokIp6qYfBGlBgIaHhyd+AUsd5hp36A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}