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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4219684e47ed3bba244f0e177c05e6ddb0fd97a75a1b6dae68ab4b41d3df3632' 
  AND token = 'Sb1mBM+vsJ4kT2VVAeRolnQIm76QmPNcQJyXah3MCXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}