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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66bd9e7eb60a26e6675855a64eeca29840b800044e0f681ed494275b4e615a43' 
  AND token = 'DZpFYvo69DAOfyRyEWCUQ4KKdYIIytNhP7GDibtD2DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}