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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9226e913f82dab49b0ad511bbd0af27841076f7d3dd93ee8b393417b4b8ab8d1' 
  AND token = 'um+oIsd8u77wlj0TiStCE/Fz4ZBs3mk4yyjRcbpwXOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}