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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730dbbdecb9af3788c43d34fcbfb8f173e5a00726ec036f671727752650949c6' 
  AND token = 'tEXlUJ9JArnZWSA+nr/geaJsVb+anBMNVW5z3Y8Pu84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}