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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b204464927c0add6d7070ce33e5efb684255d24a6a55257eb6c8179d80fe87e2' 
  AND token = 'irPBO/pN7HOMafNkTpZ5WWnpXcJT1hj0KM2IzF1Zqz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}