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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dd68d7b9149e55ecc97c88bdda3b157862671587e4db4a78a3faa05190fbecf' 
  AND token = '9UohjiNqmE/czpJk0tkmiyvQh3B0qKAQqdLdNrxR56w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}