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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f045469792e7b5596f6369b0cefb87b7a6ea31aa61b8f1aacd5485f61ba8e7' 
  AND token = 'S6QCOQK80w3o2wPdrHD29D79RemqdqspMXJnaoUn4E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}