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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cdcb7e5de4513a2082b5f305521bb287ddd7f61ec1a86a9ed048a4919485c43' 
  AND token = 's4mWKlUf3NWWGtr4pHRtr4z5kAwL1hEpfAPe4kTJuQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}