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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ad00bd76177a02c8deada08313e2e0dbdd50f391cd1ccc17c92c909ee3d8fc' 
  AND token = 'SX7j7frHV8Rin1g1RObbnVShZdxPbUQFtHV4F3gTWXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}