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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4429c3cec369e653f4b10e4db2f594a88146b5759686fd2945d3f172f7842fb8' 
  AND token = 'D5Femx9t7LcEt1m1jS0WnLw6fTfQ36S8JWMkwMXBTxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}