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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c17a6e18c1da3b33ec1120d8f0c3c0a77766dc7b4475d370241a77741615a7d' 
  AND token = 'LqDTc+aQDcUeL8uACK2IHOOIRc6mTmioM/Ujdi96cqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}