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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d93ecca5e8637dbb04dae67110e0e4f135b2454920de976a7799458cd1782c8' 
  AND token = '5NQLnNoi8PqMneeMoTnSJcPAGX/7MV28gqcb+Viuous=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}