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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6e4600f8f23aff701adc308c4d0f55e5fbca8a6d68e602a524f921e29587903' 
  AND token = 'dCLoBB3lrLonhPaGA8+bfcMjr8ofWFmcFKA/MrQB+Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}