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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d997d9e0b39e49ec66b648d3c3b458d7d68ad83738dc2bf1570a9117700d2af' 
  AND token = 'W8jTRZC6jHeTEYndY/1auzPQRi8FGXlOw1JKwTcGuR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}